cardiovascular medication
Note: If the patients HR is less than 50bpm, withhold drugs that slow the heart on the day
(e.g. amioderone, beta-blockers, digoxin, verapimil).
ACEi & Angiotensin II inhibitors
Withhold one dose before surgery.
Decisions to continue (e.g. for heart failure or poorly controlled hypertension) should be made on a case by case basis by the anaesthetist.
If withheld prior to surgery, resume as soon as possible after (within 48 hours).
Alpha blockers, alpha-2 agonists (clonidine)
& centrally acting antihypertensives (methyldopa)
Continue; give before surgery.
Antiarrhythmics
Continue; give before surgery.
Beta-blockers
Continue; give on the morning of surgery.
Calcium channel blockers
Continue, give on the morning of surgery.
Exercise caution with left ventricular dysfunction (EF <40%).
Can be withheld if bradycardia or hypotension is present.
Diuretics
Continue; give before surgery.
May be witheld where hypotension or AKI is present. Decisions should be made on a case by case basis, balancing the risks of hypertension versus effects on renal function.
Nitrates
Continue, give before surgery.
If oral route unavailable, consider nitrate patches.
Statins
Continue; give before surgery.